Telavancin and hydroxy propyl-beta-cyclodextrin clearance during continuous renal replacement therapy: an in vitro study Article (Faculty180)

cited authors

  • Patel, Jignesh; Churchwell, Mariann D; Seroogy, Julie D; Barriere, Steven L; Grio, Maricor; Mueller, Bruce A

description

  • Telavancin is a lipoglycopeptide antimicrobial agent which has been approved in Europe and has been recently FDA approved in the United States. Telavancin's parenteral solution contains hydroxy propyl-beta -cyclodextrin (HP-beta -CD) to enhance its solubility. The disposition of telavancin and HP-beta -CD during continuous renal replacement therapies (CRRT ) has not been previously reported.

publication date

  • 2009

start page

  • 745

end page

  • 51

volume

  • 32