Arginase activity is increased by thrombin: a mechanism for endothelial dysfunction in arterial thrombosis Article (Faculty180)

cited authors

  • Yang, Lin; Lewis, Chandani M; Chandrasekharan, Unnikrishnan M; Kinney, Corttrell M; Dicorleto, Paul E; Kashyap, Vikram S


  • Earlier observations implicate arterial thrombosis causing endothelial dysfunction by decreasing nitric oxide (NO) levels. NO levels are restored by regional L-arginine supplementation in animal models. The purpose of this study was to investigate the roles of thrombus components in NO generation.


publication date

  • 2006

start page

  • 817

end page

  • 26


  • 203