Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation Article (Faculty180)

cited authors

  • Marino, Jo S; Hinds, Terry D; Potter, R A; Ondrus, Eric; Onion, Jeremy L; Dowling, Abigail; McLoughlin, Thomas J; Sanchez, Edwin R; Hill, Jennifer W


  • Differentiation and fusion of skeletal muscle myoblasts into multi-nucleated myotubes is required for neonatal development and regeneration in adult skeletal muscle. Herein, we report novel findings that protein kinase C theta (PKCθ) regulates myoblast differentiation via phosphorylation of insulin receptor substrate-1 and ERK1/2.

publication date

  • 2013

published in

start page

  • 39


  • 14