Marino, Jo S; Hinds, Terry D; Potter, R A; Ondrus, Eric; Onion, Jeremy L; Dowling, Abigail; McLoughlin, Thomas J; Sanchez, Edwin R; Hill, Jennifer W
description
Differentiation and fusion of skeletal muscle myoblasts into multi-nucleated myotubes is required for neonatal development and regeneration in adult skeletal muscle. Herein, we report novel findings that protein kinase C theta (PKCθ) regulates myoblast differentiation via phosphorylation of insulin receptor substrate-1 and ERK1/2.
