Use of highly active antiretroviral therapy in patients with renal insufficiency Article (Faculty180)

cited authors

  • Duggan, Joan M; Sahloff, Eric G; Moudgal, Varsha V V


  • Antiretroviral agents, especially nucleoside reverse transcriptase inhibitors, require significant dosage adjustments in patients who have renal dysfunction and the human immunodeficiency virus (HIV). Some antiretroviral agents and fixed combination preparations are contraindicated in this population. In addition, many preferred antiretroviral regimens may be difficult to administer conveniently in patients with decreased creatinine clearance or in those receiving renal replacement therapies. Some highly active antiretroviral therapy regimens, however, can be used conveniently in patients with HIV and altered renal function.


publication date

  • 2005

published in

start page

  • 698

end page

  • 708


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