Regioselective Nickel-Catalyzed Reductive Couplings of Enones and Allenes Article (Faculty180)

cited authors

  • Li, Wei; Chen, Nan; Montgomery, John


  • lkenes made easy: In a complement to coupling processes of terminal alkynes, the reductive coupling of enones and allenes provides access to conjugate addition products that possess a 1,1‚Äźdisubstituted alkene (see scheme; cod=1,5‚Äźcyclooctadiene). The solvent composition and reducing agent must be carefully matched to allow high levels of regioselectivity to be observed.


publication date

  • 2010

start page

  • 8712


  • 49