Disease progression in sporadic inclusion body myositis: Observations in 78 patients Article (Web of Science)

abstract

  • Article abstract Functional decline for each decade at symptom onset and need for cane, walker, or wheelchair were assessed in 78 biopsy-proved patients with sporadic inclusion body myositis. Patients with disease onset between 40 and 59 years used a walker after 10.2 ± 5.8 years, whereas those with disease onset between 60 and 79 years used a walker after 5.7 ± 5.0 years (p = 0.05). Because patients progress faster to disability when symptoms begin after the age of 60, age at disease onset may define patient subsets for stratification in clinical trials.

authors

  • Peng, Angela
  • Koffman, Boyd
  • Malley, James D.
  • Dalakas, Marinos C.

publication date

  • 2000

published in

number of pages

  • 2

start page

  • 296

end page

  • 298

volume

  • 55

issue

  • 2