Multi-Body-Site Microbiome and Culture Profiling of Military Trainees Suffering from Skin and Soft Tissue Infections at Fort Benning, Georgia Article (Web of Science)

abstract

  • While it is evident that nasal colonization with S. aureus increases the likelihood of SSTI, there is a significant lack of information regarding the contribution of extranasal colonization to the overall risk of a subsequent SSTI. Furthermore, the impact of S. aureus colonization on bacterial community composition outside the nasal microbiota is unclear. Thus, this report represents the first investigation that utilized both culture and high-throughput sequencing techniques to analyze microbial dysbiosis at multiple body sites of healthy and diseased/colonized individuals. The results described here may be useful in the design of future methodologies to treat and prevent SSTIs.

authors

  • Singh, Jatinder
  • Johnson, Ryan C.
  • Schlett, Carey D.
  • Elassal, Emad M.
  • Crawford, Katrina B.
  • Mor, Deepika
  • Lanier, Jeffrey B.
  • Law, Natasha N.
  • Walters, William A.
  • Teneza-Mora, Nimfa
  • Bennett, Jason W.
  • Hall, Eric R.
  • Millar, Eugene V.
  • Ellis, Michael
  • Merrell, D. Scott

publication date

  • 2016

webpage

published in

volume

  • 1

issue

  • 5