Rescue Thrombectomy in Large Vessel Occlusion Strokes Leads to Better Outcomes than Intravenous Thrombolysis Alone: A 'Real World' Applicability of the Recent Trials
Article (Faculty180)
Nogueira, Raul G; Zaidat, Osama O O; Castonguay, Ali C; Haussen, Diogo C; Martin, C O; Holloway, William E; Mueller-Kronast, Nils; English, Joey; Linfante, Italo; Dabus, Guilherme; Malisch, Tim W; Marden, Fr A; Bozorgchami, Hormozd; Xavier, Andrew; Rai, Ansaar T; Froehler, Michael T; Badruddin, Aamir; Nguyen, Tha N; Taqi, M A; Abraham, Michael G; Janardhan, Vallabh; Yoo, Albert J; Shaltoni, Hashem; Abou-Chebl, Alex; Chen, Peng R; Britz, Gavin W; Novakovic, Roberta; Nanda, Ashish; Kaushal, Ritesh; Issa, Moh A; Frankel, Michael R; Gupta, Rishi
description
The Interventional Management of Stroke III (IMS-III) trial demonstrated no benefit for intravenous recombinant tissue plasminogen activator (IV rt-PA) followed by endovascular therapy versus IV rt-PA alone. However, IMS-III mostly included earlier generation devices. The recent thrombectomy trials have incorporated the stent-retriever technology, but their generalizability remains unknown.